Published On: 2019-11-18
chemnovatic logo, 2 bottles: purenic 99+ and synthethic nicotine, and a text: synthethic nicotine vs tobacco nicotine

The first thing that usually comes to mind when it comes to nicotine is tobacco, regardless of whether it is smoking, vaping, or pharmaceutical nicotine. As nicotine is obtained mainly from tobacco, this is a reasonable association and thus usually nicotine products are subject to the same regulations as tobacco products. Usually, but not always – there is a way to produce non-tobacco nicotine which is also called synthetic nicotine.

Tobacco nicotine

For decades, tobacco has earned its unfortunate reputation by associations with carcinogenic cigarette smoke, tar, lung, and cardiovascular diseases. The case is absolutely different for e-cigarette liquids: no burning tobacco, no smoke, or its health impacts. E-liquids manufactured with Chemnovatic’s tobacco nicotine contain pharmaceutical grade nicotine with purity of more than 99.9%. Chemnovatic’s freebase nicotine PureNic 99+ chemically distilled from tobacco leaves has gained worldwide recognition. If you would like to find out more about our pure nicotine visit our B2B platform.

What is synthetic nicotine?

Nowadays most e-liquids are manufactured with the use of tobacco nicotine, however, scientists can now produce pure nicotine without the use of tobacco in the laboratory environment. Synthetic/non-tobacco nicotine is not obtained from tobacco leaves, stems, tobacco extract, or post-production tobacco waste. Synthetic nicotine/tobacco-free nicotine is an artificial replica of traditional nicotine derived from tobacco, but it is manufactured using chemicals that do not contain any tobacco plants.

Biological characteristics of synthetic nicotine

Without getting too scientific, synthetic nicotine has the same molecular formula as traditional tobacco nicotine. Moreover, both types of nicotine share the same advantages. When it comes to the chemical composition of the substance, there is no difference between synthetic nicotine and nicotine derived from a plant. Essentially both are very similar even in terms of the nicotine satisfaction level of the end-user. The only difference between them is the process during which these are manufactured and raw materials used for this process.

By definition, synthetic nicotine is manufactured with the use of such chemical substances like, among others: ethanol, niacin, sulphuric acid. Some of the advantages that synthetic nicotine has over tobacco nicotine are the result of the low-quality pure nicotine that is available on the market. Comparing to Chemnovatic’s PureNic 99+, synthetic nicotine has very similar properties and quality, so the only advantages, in this case, are the result of the synthetic nature of this product. Both PureNic 99+ and tobacco-free nicotine do not contain nitrosamines that might be present during the extraction of nicotine from tobacco. Nitrosamines extracted from tobacco can still have a grain of plant, which creates unpleasant flavours and harshness. E-liquid manufacturers that use poor quality tobacco nicotine mask them with sweeteners and intensive flavours.

  • It is not derived from tobacco
  • It provides the same level of satisfaction as tobacco nicotine
  • It is tasteless and odorless
  • It is manufactured with the use of only certified ingredients of the highest pharmaceutical quality from reliable European suppliers.
  • There are fewer restrictions on entering new markets.
  • It meets USP and EP grade requirements.
  • The same as all our products it undergoes strict quality procedures which are confirmed by ISO 9001:2015, HACCP, and GHP/GMP standards.
a bottle of chemnovatic synthethic nicotine
  • We provide our customers with full traceability of products and additionally every batch of products that leave our facility is laboratory tested on site. You may read more about our quality control and processes here.
  • Regardless of the nicotine type, it is increasingly accepted that vaping is less dangerous than traditional smoking. A recent report from the National Academies of Sciences, Engineering and Medicine stated that “substituting e-cigarettes for combustible tobacco cigarettes reduces users’ exposure to numerous toxicants and carcinogens present in combustible tobacco cigarettes”. For more information please visit this site.

Test our nicotine

We have been receiving inquiries regarding synthetic nicotine from our customers. Although synthetic nicotine is not as thoroughly researched as tobacco-based nicotine, we have decided to add it to our product range. We would still recommend our highest quality PureNic 99+ tobacco-based nicotine but if you would like to know more about Synthetic Nicotine, please contact our Sales Team directly at

Keep in mind that nicotine is also a necessary ingredient in the market-storming nicotine pouches. If you want to learn more about these products, check our article about the key numbers regarding nicpouches’ popularity. On the other hand, if you are interested in some non-nicotine e-liquids and e-cigarettes, you can also read about them.

Dear Customers, Recently, CHEMNOVATIC has introduced synthetic nicotine into its offer. The reason for this decision was the growing number of inquiries from our current customers as well as new customers. We have made an effort to make the product available as soon as possible, but now we have encountered a problem with the availability of raw material and we need to diversify the supply chain to ensure continuity of production and recalculate prices to reflect the value of the final product due to changes in individual components. Currently, the product is not available for sale. We apologize for the inconvenience and ask for patience. We hope that the situation is only temporary, so we will keep you updated as work progresses.

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  1. Peter Vale 2020-06-21 at 01:48 - Reply

    We are looking for ways to get around the draconian laws in Australia of prohibition the importation of nicotine and Nic salts into Australia. Our New Zealand company uses 50 lit’s a week to product e liquids for the vaping market.
    From the 1 st of July Australia has banned its importation. We are wondering if we can get around this by using a synthetic product called anything other than tobacco nicotine.

    Your product fits the bill

    Please advise


    Peter Vale

  2. 2020-06-23 at 16:16 - Reply

    Hello, thank you for reaching out. Our sales specialist will contact you shortly.

  3. Eric Jin 2020-08-20 at 19:11 - Reply

    I would like get a quote for your synthetic nicotine.
    please let me know.
    Eric Jin
    714 808 7484

  4. 2020-08-24 at 08:39 - Reply

    Hello Eric, thank you for your comment. Our sales specialist will contact you shortly.

  5. javed 2020-09-18 at 16:31 - Reply

    Great job! this site is help full. i got it more information this site. thanku

  6. Mike 2020-10-06 at 15:32 - Reply

    Hey there, I was wondering if your nicotine is entirely the S isomer or if it’s a racemic mixture of R and S.

    • 2020-10-07 at 13:07 - Reply

      Hi Mike, thank you for your comment! At the moment, we have withdrawn synthetic nicotine from the offer. This project is currently suspended because we are refining the technology. When we reintroduce synthetic nicotine to our offer, we will post this information on our website and communicate this fact via e-mail to our subscribers, so be sure to subscribe to the newsletter here:

  7. Jay 2020-10-15 at 13:36 - Reply

    Want to buy synthetic Tabacoo

    • 2020-10-15 at 14:07 - Reply

      Hi Jay, thank you for your comment! At the moment, we have withdrawn synthetic nicotine from the offer. This project is currently suspended because we are refining the technology. When we reintroduce synthetic nicotine to our offer, we will post this information on our website and communicate this fact via e-mail to our subscribers, so be sure to subscribe to the newsletter here:

  8. Taylor Hicken 2020-11-06 at 03:11 - Reply

    It’s interesting to know that synthetic nicotine does not contain any tobacco plants at all as it is made from chemicals solely. It is a good alternative as it does provide the same level of satisfaction for the users who are used with tobacco nicotine. I would like to think if someone wants to avoid the danger of tobacco, it should opt for the synthetic one that offers the same function.

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